NZM (2410) [Mus musculus]

Species
Strain Acy1b, Car2a, Es1b, Es3c, Esdb, Ggca, H2-T18c, H6pd1b, Gpi1a, Gus-sb, Hbbd, Idh1a, Ldr1a, Mod1b, Mpi1b, Pnpa, Pep3b, Pgm1b, Pnpa, Sod1a, Trfb
Source
Summary
  • By six months of age approximately 80% of mice show anti-dsDNA IgG antibodies present in the sera
  • Approximately 80% of males and females develop glomerulonephritis by one year of age
  • Deficient in C5(Hco) and carries the pink-eyed dilution gene
  • Valuable for investigating autoimmunity and the genetic components and pathology of murine systemic lupus erythematosus (SLE)
Keywords

Genes

Gene Alias Organism Keywords Relationships
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) D17H6S56E-2, D17H6S56E2, Dmapl, Dmpkap, G7b, MGC13889, Sm-X5, SmX5, snRNP 4